Distributed SQL database (CockroachDB). NYC. Benchmark + GV + Redpoint. $5B valuation 2021.

Pfizer is one of the world's premier biopharmaceutical companies, headquartered in New York, NY. The company discovers, develops, and delivers medicines, vaccines, and consumer healthcare products globally, with more than 10,000 employees worldwide.

Crypto asset manager (Bitcoin Trust, Ethereum Trust); confidentially filed IPO recently per The Information

Cloud-based manufacturing-execution software platform for pharmaceutical and life-sciences manufacturers to manage drug production end-to-end.

SMS and email marketing automation platform. NYC. Sequoia + Coatue. $10B valuation 2021. 8,000+ brands.

Employee benefits platform. YC W20. Co-founded by Kabir Soorya (CTO). New York NY. Streamlines HR benefits through mobile app.

Automated investing and financial planning platform. NYC. Bessemer + Kinnevik. 800K+ customers, $40B+ AUM. Pioneer of robo-advisors.

Crypto wallet and trading services; 43M+ users; confidentially filed IPO May 2026

CA Technologies was an American multinational enterprise software company headquartered in New York, specializing in mainframe software, IT management, and DevOps solutions. Founded in 1976, it was acquired by Broadcom in 2018 and now operates as a Broadcom company.

Manufactures Greek yogurt and other dairy and plant-based food products; founder Hamdi Ulukaya remains majority owner.

Community-based healthcare for Medicaid/low-income populations. NYC. General Catalyst + Alphabet. Raised $160M 2022. Addresses health equity.

Cloaked — consumer and enterprise digital-privacy platform (virtual identities, data removal, monitoring, call screening). Founded 2020 by brothers Arjun and Abhijay Bhatnagar; Lowell, MA. $400M+ raised; Series B led by General Catalyst and Liberty City Ventures, with Lux Capital, Human Capital, DuckDuckGo.

CRM and civic engagement platform for campaigns, nonprofits, and advocacy groups. People-centric data platform combining mobilization and engagement tools. Acquired by Murmuration in 2019 as their core campaign management technology (powering m{insights platform). $4.3M raised. Founded NYC.

Cloud monitoring and analytics platform. NYC. OpenView Venture Partners. IPO Sept 2019 at $7.8B. NASDAQ: DDOG. $40B+ market cap.

Brooklyn startup using AI to design and manufacture printed circuit boards (PCBs) in the US — attacking one of the most overlooked layers of the tech stack (PCBs power smartphones, satellites, medical devices, autonomous systems). Founded ~2024. Customers include Physical Intelligence and Saronic; partnered with Anthropic to help Claude become a better electrical engineer. Ambition: make hardware as nimble as software.

Makes BuildOS, an AI platform that auto-generates animated, interactive manufacturing work instructions and bills-of-process directly from CAD models for aerospace, defense, and automotive OEMs.

Oncology data and analytics platform. NYC. First Round Capital + Google Ventures. Acquired by Roche $1.9B 2018.