ActionSprout is a Seattle-based company that built a platform helping nonprofits maximize their Facebook presence through custom action tools such as donation collection, petition signing, and supporter engagement beyond standard likes and shares. Founded around 2012, the company focused on enabling nonprofits to convert social media audiences into active participants.

AppThwack was a Portland-based cloud testing startup that provided automated mobile app testing on real physical devices, supporting Android, iOS, and web apps across more than 200 phones and tablets. The company partnered with In-Q-Tel (IQT) to expand its app testing technology and integrated with CI tools like Jenkins. AppThwack was acquired by Amazon and became part of AWS Device Farm.

Apptio, headquartered in Bellevue, Washington, provides Technology Business Management (TBM) software that helps organizations translate technology investments into business value and optimize IT spend. IBM acquired Apptio in August 2023 for $4.6 billion; the company now operates as IBM Apptio.

Blendoor is a diversity analytics and inclusive recruiting software company that mitigates unconscious bias in hiring. Its platform sources job candidates from hundreds of strategic partners and provides diversity and inclusion analytics, including a BlendScore rating for companies. Founded by Stephanie Lampkin, Blendoor enables companies to attract and retain diverse talent.

Brandlive is a Portland, Oregon-based SaaS company that develops virtual-event and video production software, bringing television-quality broadcast capabilities to corporate communications and live events. The company partners with large enterprises to create and stream branded content. It was founded and operates as a standalone software-and-services platform.

CleanHaus is a property management software company that connects short-term rental hosts' Airbnb and Vrbo bookings directly to their cleaning crews, automatically scheduling turnovers when reservations are created or modified. Built by hosts for hosts, the platform aims to eliminate missed cleanings and streamline turnover coordination.

Cloud Campaign is a white-label social media management platform built for marketing agencies and SaaS products. It enables agencies to schedule, publish, and analyze content across Facebook, Instagram, LinkedIn, TikTok, and other channels from a single calendar, with AI-powered automation and client approval workflows.

DeepSurface is a risk-based, predictive vulnerability management platform that helps cybersecurity teams discover, analyze, and remediate vulnerabilities by contextualizing them within an organization's unique environment. The company was acquired by AttackIQ in February 2025 to bolster AttackIQ's Adversarial Exposure Validation solutions.

Digs is an AI-powered software platform for residential home builders that centralizes file management, pre-construction planning, and collaboration among builders, vendors, and homeowners to reduce re-work and improve the homeowner experience.

Drypowder is a financial operating system for the building materials and construction industries that automates accounts receivable and collections workflows and digitizes billing. The platform integrates with ERP systems to help construction suppliers streamline payment collection and centralize AR data. Drypowder was acquired by ECI Software Solutions.

Elemental Technologies was a Portland, Oregon-based software company (founded 2006) that developed software-defined video solutions for encoding, transcoding, and delivering multiscreen video. The company reported $49.2 million in revenue in 2014 and was acquired by Amazon in 2015, becoming AWS Elemental.

Esri is a Redlands, California-based company and global leader in geographic information system (GIS) software, best known for its ArcGIS platform. Founded in 1969, Esri provides enterprise geospatial technology that integrates and connects data through the context of geography for mapping and spatial analytics.

FlexPoint is an accounts receivable and payments automation platform purpose-built for managed service providers (MSPs) and the businesses they serve. It consolidates billing operations under one roof, enabling MSPs to streamline payment collection and financial workflows.

FundMiner is a fund management and donor reporting platform for fundraising organizations. It aggregates and organizes siloed fund data into a single workflow, connecting existing systems to unify fund management, donor reporting, and stakeholder engagement. It is available as a Blackbaud marketplace application.

Groopit is a real-time intelligence platform that aggregates insights from employees to help organizations solve critical business problems affecting revenue, customer satisfaction, product development, and competitive positioning. The company was founded on the premise that complex problems require strong leadership and extended team collaboration.

GrowthPlug is a practice growth and optimization SaaS platform focused on helping healthcare practices accelerate new patient acquisition. It offers mobile-optimized websites, business listings management, social media publishing, and reputation management tools. GrowthPlug was acquired by PracticeTek in 2022.

Hubly is a practice management software platform designed for financial advisory firms, providing workflow management, task tracking, automations, and collaboration tools. Its operating system enables advisory firms to deliver a high-touch household experience at scale while ensuring nothing falls through the cracks.

Hydrolix is a real-time data platform that delivers sub-second analytics at global scale, addressing runaway costs, slow query performance, and fragile clusters. Founded in 2018, the platform enables real-time analytics across globally distributed data at internet scale, serving use cases ranging from servers and applications to large-scale observability workloads.

Instinct Science is an animal health technology company providing veterinary practice management software designed to help hospitals stay efficient, ensure patient safety, and capture every charge. Its platform supports veterinarians and hospital staff with workflow tools, and in January 2026 acquired ScribbleVet to advance intelligent veterinary practice management.

Invio is a Seattle-based startup that develops FDA-compliant, cloud-based software to automate clinical trial workflows, replacing traditional paper and manual monitoring processes. The company makes clinical trials safer and faster through enterprise software for remote and automated trial monitoring. Invio was selected as the first company out of Madrona Venture Labs' accelerator in 2018.