Strangpresse is a Warren, Ohio-based manufacturer of high-performance thermoplastic extruders for 3D printing and additive manufacturing applications. Founded in 2014 and located at 900 Pine Ave SE, the company designs lightweight, fully controllable extrusion heads. Strangpresse has a licensing partnership with Oak Ridge National Laboratory (ORNL) for its extruder technology.

Tailored Alloys is a Youngstown, Ohio-based advanced manufacturing company developing software and hardware to unlock the potential of laser powder bed fusion (metal 3D printing) for applications including hypersonic and other high-performance use cases. The company's patent-pending process centers on alloy evaluation and optimization, and it has received support from the Youngstown Business Incubator (YBI).

GM–LG Energy Solution JV EV-battery gigafactory in Lordstown OH (operating) — cornerstone of the Mahoning Valley's auto/EV reinvention.