Adaptive Biotechnologies is a Seattle-based pioneer in immune-driven medicine that harnesses the adaptive immune system as a natural diagnostic and therapeutic tool. The company decodes and deploys the immune system's capabilities to improve patient lives and propel a paradigm shift in medicine.

Seattle WA. Non-profit neuroscience research institute founded by Paul Allen (2003, $100M founding gift — his first major science philanthropy). Part of Allen Institute umbrella (alongside AI2 and Allen Institute for Cell Science). Flagship product: Allen Brain Atlas — free, open-access database of gene expression in mouse and human brains, used by 90%+ of neuroscience researchers globally. Allen Cell Types Database. Allen Mouse Brain Connectivity Atlas. $100M+ annual budget from Paul G. Allen estate. Deep UW Medicine partnership. CEO: Christof Koch (leading consciousness researcher, 2011-2023); now Allan Jones. Brain science → AI feedback loop: Brain Atlas data used extensively in training neural network architectures. Precursor intellectual lineage to AI2. Both AIBS and AI2 are Paul Allen legacy institutions — managed under same philanthropic umbrella.

Industrial protein-design company using physics-based computational design, AI, and lab automation; co-founded by Nobel laureate David Baker out of the University of Washington's Institute for Protein Design.

Sana Biotechnology is a Seattle-based biopharmaceutical company focused on engineering cells to repair and control genes or replace missing and damaged cells to address the underlying causes of disease. Founded in early 2019, it has grown to over 350 employees across Seattle, Cambridge, and South San Francisco. The company is publicly traded and conducts research in cell and gene therapy.

Zenoti is a Bellevue, Washington-based company providing an all-in-one cloud software platform for the beauty, wellness, and fitness industry, including salons, spas, and med spas. Its platform automates bookings, lead nurturing, and revenue management for over 30,000 businesses. Zenoti is headquartered at 15395 SE 30th Pl, Bellevue, WA.