PredxBio is an AI-driven, tissue-based biomarker company that uses spatial analytics and artificial intelligence to transform tumor biopsy images into predictive biomarkers, powering drug discovery and development decisions for biopharma and diagnostics clients.

Peptilogics is a clinical-stage surgical therapeutics company developing novel anti-biofilm drugs to cure and prevent medical device-related infections (MDRI). Its lead asset, Zaloganan, advanced into a pivotal clinical trial following a $78 million funding round announced in October 2025.

Push2Spin Technologies, Inc. is a medical device company founded by Pitt surgeons Jeff and Beth Gusenoff, dedicated to developing and commercializing innovative devices for the global fat transfer market. Its flagship device streamlines the fat grafting preparation process, significantly reducing procedure time for plastic and podiatric surgeons.

Accel Diagnostics is a medical diagnostics company developing proprietary point-of-care diagnostic assays for the diagnosis, monitoring, and management of various conditions. The company has proposed an innovative blood diagnostic test to aid the triage of patients presenting with head injuries, supported by SBIR funding.

Accipiter Systems, Inc. is a computer networking company specializing in optical and PCIe solutions for edge and fog computing. The company develops high-performance interconnect technologies designed to enable the next generation of real-time computing infrastructure.

Admirra is a CRM and workflow management platform purpose-built for mental health practices. The company helps mental health practice owners boost revenue and enhance access to care through comprehensive business solutions, and is a portfolio company of AlphaLab.

Adrich is a Pittsburgh-based IoT connected eCommerce technology company that delivers product usage and behavior insights along with sustainable replenishment solutions. The company offers patented product trackers that adhere to any type or size of packaging, combined with customized software.

AdSkate is an AI-powered creative intelligence platform that helps brands analyze and optimize advertising performance. Founded by industry veterans, AdSkate bridges creativity and data to help brands optimize ad performance 5x faster while increasing return on ad spend (ROAS) by up to 45%.

Advanced Optronics is a medical device company co-founded by engineers from Carnegie Mellon University developing flexible, biocompatible micro-scale sensor systems for real-time AI guidance in surgery. Founded in 2021 to commercialize CMU research, the company has received NSF grant support.

Aethon, Inc. is a provider of autonomous mobile robots for the healthcare and hospitality markets, automating routine delivery and transportation tasks to support clinical teams and staff. The company is a subsidiary of ST Engineering and serves hospitals with secure, autonomous delivery solutions.

Agot AI is a computer vision platform company serving enterprise foodservice and fast-food operators, using AI to improve order accuracy and operational efficiency. The company raised a $10 million funding round in September 2021 to expand its technology in the restaurant industry.

Allpoint Systems, LLC is a software and data processing company that offers solutions for collecting and processing LiDAR (laser) data. The company serves customers who work with geospatial and point-cloud datasets.

Allvision IO specializes in high-definition, time-based asset inventories for infrastructure, mobility, and transportation, using machine learning and automated data capture. The company provides continuously updated digital infrastructure maps for municipalities, public agencies, and private clients.

ALung Technologies, Inc. is a Pittsburgh-based medical device company that developed low-flow extracorporeal carbon dioxide removal (ECCO2R) technologies for treating patients with respiratory failure. The company originated from the University of Pittsburgh and was acquired by LivaNova PLC in July 2022.

Aquatonomy is a full-stack robotics company redefining underwater inspection through autonomy and AI-powered data intelligence. Its autonomous underwater vehicles perform 3D inspections in any visibility, turning complex environments such as bridges, dams, and ship hulls into precise, measurement-grade digital twins.

Arieca is a Pittsburgh, PA-based leader in advanced thermal interface materials (TIMs) for cooling high-performance semiconductor chips. Its patented Liquid Metal Embedded Elastomer (LMEE) products combine superior thermal performance with exceptional mechanical reliability for sustainable computing applications.

ARIEL Precision Medicine is a Pittsburgh, PA-based company pioneering the integration of genomic and clinical data to transform complex data into actionable healthcare insights. It has developed decision-support tools that integrate complex genetics into clinical decision making, focused on chronic diseases with high unmet need.

Arin Technologies provides integrated ultra-wideband (UWB) technology for real-time location tracking and situational awareness around material handling equipment. The company offers its ARINAlert system targeting forklift safety and industrial environments.

Astria Biosciences is a Pittsburgh-based startup developing blood-based diagnostics and small molecule inhibitors to combat cerebrovascular and neurovascular diseases. The company targets conditions such as aneurysm and craniofacial synostosis and has received NSF support.

AthleteTrax, LLC is a Pittsburgh, PA-based company that provides cloud-based athletic and sports facility management software. Its platform covers scheduling, payments, rentals, bookings, member management, and point-of-sale for ice rinks, multi-sport facilities, and recreational leagues.