Capital Innovators operates an accelerator program that provides seed funding, mentorship, and resources to startups, while also managing venture investments in early-stage companies and offering corporate innovation services including startup sourcing and accelerator programs. The organization has scaled over 180 startups globally and works with clients ranging from startups to global enterprises and government entities.

Kansas City's flagship non-dilutive startup grant competition, run through EDCKC. Invests $500K-$1M+ annually; since its 2015 launch has supported 137 companies, helping attract $650M+ in follow-on capital and create 1,640 jobs, with more than two-thirds women- or minority-led. 2026 cohort: eight companies, $60,000 each.

Arch Grants is a venture philanthropy organization that provides equity-free startup grants and support services to entrepreneurs launching businesses in St. Louis. Since 2012, the organization has funded over 291 companies through a competitive grants program designed to accelerate economic development and create jobs in the region.

Cultivation Capital is a venture capital firm that invests in early-stage companies from Series Seed through Series B across life sciences, software, agriculture, and geospatial technology sectors. The firm provides capital in the $100k to $3.5M range alongside access to its network of partners and investors to help portfolio companies scale.

Kansas City-based venture capital firm investing in early-stage startups across the greater Midwest, with a focus on life sciences capital.

Early-stage venture capital firm based in Kansas City -- "Partners for the Underestimated" -- invests in tech leaders across the broader Flyover/Midwest region.

iSelect Fund is a venture capital firm that invests in agricultural technology, soil and crop health solutions, and health-focused data analysis technologies. The fund focuses on companies addressing global protein demand, improving food nutrition and affordability, farmer profitability, and treating cardio-metabolic diseases.

The only traditional venture capital firm focused specifically on the Kansas City region; manages over $100 million, investing in early-stage technology companies with a strategic connection to KC.

Missouri Technology Corporation is a public-private partnership created by the Missouri General Assembly to promote entrepreneurship and foster the growth of new and emerging high-tech companies, with a focus on the life sciences and technology industries. MTC provides venture capital investments through its IDEA Fund Program and supports the entrepreneurial ecosystem through various grant programs including the MOBEC Grant Program, Physical Infrastructure Grant Program, and Regional Node Gra...

NYC-based frontier tech VC. Deep service academy network — primary VC partner to West Point entrepreneur ecosystem. First investor in Academy Investor Network. Focus: dual-use technology, national security, defense tech, deep tech. Strong USMA/West Point relationships. Annual West Point Entrepreneur Summit participation. [merged from 1385]: Veteran founder focus. Seed.

St. Louis Arch Angels is an angel investment group that has invested over $100 million in more than 100 early-stage businesses since 2005. The organization's members are business leaders, engineers, physicians, and scientists who provide capital and support to new ventures in the St. Louis region.

WILsquare Capital is a St. Louis-based private equity firm that acquires and grows lower-middle market businesses in the Midwest and Southern U.S., with a focus on business services, niche manufacturing, distribution, and technology companies. The firm was established by private equity and operational executives to provide financial capital and operating expertise to its portfolio companies.