Aethon, Inc. is a provider of autonomous mobile robots for the healthcare and hospitality markets, automating routine delivery and transportation tasks to support clinical teams and staff. The company is a subsidiary of ST Engineering and serves hospitals with secure, autonomous delivery solutions.

Angler Labs (also known as ANGLR) is a Pittsburgh-based company that developed a mobile, web, and connected sensor platform to enhance the sport fishing experience. Its flagship app allows fishing enthusiasts to automatically track and log trip information, and was recognized as a first-of-its-kind tracking technology.

Arieca is a Pittsburgh, PA-based leader in advanced thermal interface materials (TIMs) for cooling high-performance semiconductor chips. Its patented Liquid Metal Embedded Elastomer (LMEE) products combine superior thermal performance with exceptional mechanical reliability for sustainable computing applications.

Arin Technologies provides integrated ultra-wideband (UWB) technology for real-time location tracking and situational awareness around material handling equipment. The company offers its ARINAlert system targeting forklift safety and industrial environments.

ATRP Solutions, Inc. was a Pittsburgh-based specialty polymer company that designed and delivered tailored polymers to improve product performance in applications such as oil field chemicals and lubricant additives. The company was acquired by Pilot Chemical Company in July 2017 and subsequently renamed Pilot Polymer Technologies, Inc.

Bedrock Semiconductor Inc. is headquartered in Hummelstown, Pennsylvania, and develops GaN-on-GaN semiconductor devices to increase the efficiency of electrical systems including data centers, electric vehicles, and renewable energy infrastructure.

Beyond Reach Labs builds deployable solar arrays that deliver orders-of-magnitude more power per launch, providing scalable energy infrastructure for orbital and space applications. Founded in 2023 by Pele Collins and Mitchell Fogelson, the company is a Y Combinator W26 alumnus.

Biointerphase is a mission-driven bioengineering studio dedicated to restoring and reinforcing biological needs through sustainable biointerfaces. The company combines bioengineering with sustainable design to create impactful products for healthcare, with roots at the University of Pittsburgh.

BIOSAFE, Inc. was a polymer manufacturer developing personal care polymers for personal care, consumer, and healthcare products. The company was acquired by Gelest, a specialty silicone and metal-organic chemical company.

ChemDAQ manufactures hazardous gas monitoring equipment for potentially harmful chemicals including ethylene oxide (EtO), hydrogen peroxide (H2O2), and peracetic acid (PAA), primarily for healthcare and industrial workplaces. The company partners with distributors such as Zee Company to provide continuous monitoring solutions that protect workers from chemical exposure.

DisSolves, Inc. is a material science company that has developed patented biodegradable and edible film technology using food-grade, GRAS-certified components, enabling dissolvable, plastic-free packaging with no mess or measuring. The company was acquired by Generation Food Rural Partners and subsequently merged with TerraSafe Materials, Inc. in 2025.

FlowCellutions is an early-stage clean energy tech startup that provides real-time monitoring and diagnostic tools for grid-scale battery systems. Its first-of-its-kind sensor technology targets a $45B market in energy storage. The company is a member of Greentown Labs.

FreshTemp provides real-time IoT temperature and operational task monitoring technology for food service businesses to improve food safety compliance, reduce food waste, and enable HACCP management. The company's platform was subsequently integrated into SmartSense by Digi.

Gus Gear makes wearable securement clothing to protect implanted medical devices such as central catheters and feeding tubes, improving safety and quality of life for patients facing medical challenges. The company was founded by Sarah Palya, whose personal experience with her son Gus inspired the product line.

HeadStrait Labs is a Pennsylvania-based life sciences company focused on overlooked areas of healthcare, starting with emergency transport. The company is building the EVAC-1 with SMARTmotion technology to bring real-time data and accountability to patient handling and transport.

Humotech is a Pittsburgh-based medtech company that blends human movement science, engineering, robotics, and data to advance personalized prosthetic care. Its Caplex® platform offers a clinical prosthetic foot trialing service that enables people with limb loss to rapidly compare and test different prosthetic feet in real-time before selecting a device.

INTEG Process Group, Inc. is a hardware automation company founded in 1999 that designs and manufactures the JNIOR, a flexible automation controller with digital and analog I/O, Ethernet, and serial connectivity. The company also provides industry-specific software utilities and system-specific integration solutions.

JuneBrain Inc. is a Maryland-based medical technology company that develops telehealth OCT (optical coherence tomography) devices and AI software for remote monitoring of neurological and retinal diseases. The company's mission is to empower the ophthalmology and neurology communities through accessible monitoring of eye and brain health.

Lead-In Record Co. is a Pittsburgh-based company that uses robotics to manufacture vinyl records on-demand for independent artists. Founded by a team of engineers and musicians, it serves as a manufacturer and distributor enabling indie artists to produce records through an automated vinyl production process.

Liquid X Printed Metals, Inc. is an advanced materials manufacturer headquartered in Pittsburgh, Pennsylvania that produces functional metallic inks for printed and flexible electronics. The company takes electronic applications from prototype to full production using its proprietary conductive ink technology.