Global pharma; Puerto Rico (U.S.) manufacturing in Barceloneta and Jayuya.

Global biotech; flagship Puerto Rico (U.S.) plant in Juncos produces a large share of Amgen product.

Fast-acting sublingual drug-delivery formulations. Puerto Rico (U.S.) pharma.

Global pharma (US base Wilmington DE); Puerto Rico (U.S.) manufacturing in Guayama.

Global med-device/pharma; Puerto Rico (U.S.) manufacturing in Aibonito, Jayuya, Guayama.

Biosimilar Solutions is a global biosimilar company headquartered in Aguadilla, Puerto Rico, committed to expanding patient access to life-changing biologic medicines. The company operates in a PRIDCO facility in Aguadilla and announced in 2026 a GMP biomanufacturing plant exceeding 95,000 sq ft of cleanroom space in partnership with OcyonBio.

Global med-device; Puerto Rico (U.S.) plant in Dorado produces ~100% of its global cardiac-rhythm-management leads.

Global pharma; Puerto Rico (U.S.) biologics in Manati and Humacao (Opdivo, Yervoy, Eliquis).

Cell therapy and cancer immunotherapy. Puerto Rico (U.S.) biotech — the overlooked local life-sciences economy.

Global pharma; major Puerto Rico (U.S.) manufacturing — insulin/biologics (Carolina) and Mayaguez.

Johnson & Johnson is a global healthcare company headquartered in New Brunswick, NJ, focused on preventing and curing complex diseases through smarter, less invasive treatments and personalized solutions. It was the first innovative healthcare company founded in New Jersey.

GTPase-inhibitor oncology compounds (R&D stage). Puerto Rico (U.S.) biotech.

Medtronic is a global medical device company with operational headquarters in Minneapolis, Minnesota and legal headquarters in Ireland. It develops and manufactures a broad portfolio of medical technologies spanning cardiac, neurological, surgical, and diabetes care. Medtronic is one of the largest medical device companies in the world and trades publicly on the NYSE.

North Jersey pharma giant (Rahway, NJ HQ) — the NYC-metro medicine chest.

Specialty pharma in women health / menopausal treatment. Puerto Rico (U.S.).

Contract manufacturing of small-molecule pharmaceuticals; a 40-plus-year plant. Puerto Rico (U.S.).

PDMO for gene and cell therapy — cGMP viral vectors and cell processing. Puerto Rico (U.S.).

Pace Life Sciences is a contract development and manufacturing organization (CDMO) providing analytical and lab services, including FDA-registered laboratory capabilities. The company operates a site in San German, Puerto Rico, recognized by PharmaSource as a Top CDMO. Its San German facility has received a positive inspection from the FDA.

Pfizer is one of the world's premier biopharmaceutical companies, headquartered in New York, NY. The company discovers, develops, and delivers medicines, vaccines, and consumer healthcare products globally, with more than 10,000 employees worldwide.

Viant Medical is a global design and manufacturing services partner for the medtech industry, developing and manufacturing life-changing medical devices. The company operates a facility in Vega Baja, Puerto Rico, focused on drug delivery and other medical device manufacturing. Viant serves as a trusted partner to medtech companies worldwide.