Nimble Energy is a Triangle, North Carolina-based building energy management technology company whose AI-enabled Empower platform helps building operators streamline energy and utility management and optimize operational costs. The company closed a seed funding round led by Cofounders Capital in April 2025.

Pairwise is agriculture's leading plant CRISPR company, founded in 2017 and based in Durham, NC. The company uses its proprietary Fulcrum™ platform, which combines advanced CRISPR tools and AI, to deliver innovations that make food easier to grow and better to eat. Pairwise applies genomics and data science to improve crops through highly collaborative, cross-functional teams.

Urban Offsets is a Greensboro, North Carolina company that builds local carbon markets by helping colleges and universities meet their Climate Action Plans through partnerships with cities to plant trees and generate urban carbon credits. The company has partnered with organizations such as TreesCharlotte to create verifiable local carbon offset projects.