AirSeal CardioVascular Inc. is a medical diagnostics company headquartered at 4340 Duncan Ave, St. Louis, MO, focused on transforming the detection and management of peripheral arterial disease (PAD). The company was founded in 2022 and is privately held.

St. Louis agricultural-science division (the former Monsanto) — global crop science.

Centene Corporation is a leading managed care organization headquartered in St. Louis, Missouri, providing access to high-quality healthcare solutions for families and individuals. The company operates as a government-sponsored managed care plan across multiple states. Its corporate headquarters is located at 7700 Forsyth Boulevard, St. Louis, MO 63105.