4MATIV Technologies is a transportation technology and service platform headquartered in St. Paul, MN that enables a multi-modal approach to uncovering efficiencies, optimizing modal mix and routes, and cutting costs. The company manages transportation services for schools and charter networks in the Minneapolis-St. Paul area.

akoyaGO is a Minneapolis, MN-based software company providing comprehensive reporting and data management tools for philanthropic foundations. Founded with roots tracing to 1978, the company is headquartered at 2626 in Minneapolis and focuses on amplifying the impact of grantmaking organizations through purpose-built software.

Ambient Intelligence is a healthcare technology company headquartered in Minneapolis, MN that develops ambient sensor systems for long-term care settings. Its platform detects patient movement without wearables or cameras, aiming to improve patient outcomes in skilled nursing and care facilities.

Axon Athletics is a Minneapolis, Minnesota-based company founded in 2022 that provides mental training tools and resources for athletes. The company is focused on developing the mental performance side of athletic training to help athletes build confidence and reach peak performance.

BetterYou is a St. Paul, Minnesota-based startup offering a personalized productivity and wellness coaching app that helps users build healthier phone-use habits and achieve their goals. The company raised $6 million in Series A funding in December 2023.

Bizzy Coffee is a Minneapolis-based certified organic cold brew coffee brand offering ready-to-drink cold brew bottles, coarse grounds, cold brew bags, and whole beans. In 2021, the company raised nearly $7 million to build a new Minnesota production facility and expand nationally.

Branch Messenger (doing business as Branch) is a Minneapolis, MN-based fintech company that delivers faster, more flexible payment options for businesses to pay their workers. The platform empowers employees, gig workers, and independent contractors with easy access to earnings and digital banking tools.

Cadre is a social platform for mental health support, headquartered in the Minneapolis-St. Paul area, connecting individuals with vetted therapists and coaches 24/7. The platform allows mental health professionals to reach users at scale through a social media-inspired interface.

drvn is a scalable ground travel reservation and management platform serving individual rides, corporate travel, and large-scale events with onsite coordination. The platform uses patented AI-powered technology to streamline ground transportation logistics for executives and corporate clients globally.

EmpowerU is a Minnesota-based social-emotional learning platform that delivers an evidence-based turnkey system to counselors, teachers, and schools to support student mental health and build resilience. The company has expanded to thousands of students across more than 50 districts, with growth in Tennessee, Nebraska, and Wisconsin.

Gametime Hero is a community organizing software platform that helps sports organizers connect and manage recreational sports and community events. Headquartered in Minneapolis, Minnesota, it provides an all-in-one solution for event management, registration, payments, and communication, and is free to start.

GEM Sleep is a virtual sleep apnea clinic headquartered in White Bear Lake, Minnesota, founded in 2022. It offers at-home sleep apnea diagnosis, treatment, and support including CPAP machine bundles, with services accepted in-network by major insurers.

Gravie is a Minneapolis, MN-based health benefits company offering level-funded health plans and a market-leading Individual Coverage Health Reimbursement Arrangement (ICHRA) solution for small and midsize businesses. The company is focused on creating health benefits that actually work for employers and their teams.

Herself Health is a primary care practice designed specifically for women on Medicare, operating clinics in the St. Paul, Minnesota area. The company offers in-person primary healthcare services with locations including Highland Park in St. Paul, open Monday through Friday.

Inspectorio is an AI-powered supply chain management platform headquartered in Minneapolis, Minnesota that helps brands and retailers transform production chain operations, automate compliance tasks, and accelerate decisions. The company was named a Top 100 Global Company on the Red Herring 2022 Global Company List.

Itiliti Health is an Eden Prairie, Minnesota-based healthcare technology company that helps health insurance payers streamline prior authorization and enable efficient real-time collaboration between payers and providers. The company was named a preferred vendor by the Association for Community Affiliated Plans (ACAP) in 2022.

Jay Victoria is an LGBTQ+ women-led apparel company based in Minneapolis, MN, providing stylish wardrobe essentials designed to empower diverse body types. The company offers menswear-inspired fashion for plus-size bodies and the LGBTQ+ community.

Rochester MN (+ Phoenix + Jacksonville). $17.6B revenue (2023). Not-for-profit academic medical center. Mayo Clinic Ventures: commercialization arm, 150+ licenses/yr, $100M+ annual IP revenue. Major AI/digital health partnerships (Google, Microsoft, Epic). "Destination medicine" model. Research budget $900M+.

Nested Knowledge is a Saint Paul, MN-based software company offering AI-assisted tools for systematic literature review and meta-analysis, serving medical researchers and evidence synthesis teams. Its platform accelerates, automates, and enables collaboration across literature review workflows. In 2024 it partnered with Research Solutions to provide full-text article access.

Nice Healthcare is a Roseville, Minnesota-based integrated primary care company that delivers primary care, mental health, and physical therapy services to patients at home, at the office, or virtually. Its clinic model is designed to treat nearly all everyday healthcare needs in the most convenient setting for the patient.