Crowd Supply is a Portland, Oregon-based crowdfunding platform focused on novel open-source and independent hardware products. Now a division of Mouser Electronics, the platform claims over twice the success rate of Kickstarter and Indiegogo for hardware campaigns.

Caravel Bio is a Portland, Oregon–based synthetic biology startup building a novel protein evolution platform that creates proteins exceeding nature's bounds to serve as new protein machines. The company targets applications in critical minerals, carbon capture, and industrial processes using cell-free protein engineering methods.

GrowthPlug is a practice growth and optimization SaaS platform focused on helping healthcare practices accelerate new patient acquisition. It offers mobile-optimized websites, business listings management, social media publishing, and reputation management tools. GrowthPlug was acquired by PracticeTek in 2022.

Abaxx Technologies operates Abaxx Exchange, a commodity futures exchange and clearinghouse that delivers smarter market infrastructure for global commodity markets. The exchange introduces centrally-cleared, physically-deliverable futures and derivatives for LNG, carbon, battery materials, and gold, providing better price discovery and risk management.

Absci is a clinical-stage biopharmaceutical company headquartered in Vancouver, Washington that uses generative AI to design and develop differentiated drug therapeutics. Founded in 2011, Absci is publicly traded on Nasdaq (ABSI).

Acolyte Health is a patient engagement company that delivers personalized instructions, connections, and education to improve health outcomes. The company provides solutions that support patients through their care journey with tailored communications and resources.

ActionSprout is a Seattle-based company that built a platform helping nonprofits maximize their Facebook presence through custom action tools such as donation collection, petition signing, and supporter engagement beyond standard likes and shares. Founded around 2012, the company focused on enabling nonprofits to convert social media audiences into active participants.

ADT Inc. is an American security company headquartered in Boca Raton, Florida, that provides residential and small business electronic security, fire protection, and smart home solutions across the United States. It is widely recognized as America's #1 home alarm provider, offering burglar alarms, life safety systems, and interactive smart home technology.

AheadComputing is a Beaverton, Oregon-based semiconductor company building high-performance RISC-V processors for AI, cloud, and edge computing. The company was founded by Intel CPU architects with over 100 years of combined experience in microprocessor design.

AiStrike is a cybersecurity company offering a Composite AI platform that automates and unifies every stage of the security operations center (SOC) lifecycle. The platform deploys agentic AI to help organizations reduce alert noise, accelerate incident response, and modernize security operations without the cost and complexity of traditional managed detection and response.

AppThwack was a Portland-based cloud testing startup that provided automated mobile app testing on real physical devices, supporting Android, iOS, and web apps across more than 200 phones and tablets. The company partnered with In-Q-Tel (IQT) to expand its app testing technology and integrated with CI tools like Jenkins. AppThwack was acquired by Amazon and became part of AWS Device Farm.

Apptio, headquartered in Bellevue, Washington, provides Technology Business Management (TBM) software that helps organizations translate technology investments into business value and optimize IT spend. IBM acquired Apptio in August 2023 for $4.6 billion; the company now operates as IBM Apptio.

Archer Aviation designs and develops electric vertical takeoff and landing (eVTOL) aircraft for urban air mobility networks. Its flagship production aircraft, Midnight, carries four passengers and one pilot up to 60 miles at speeds of up to 150 mph. The company is headquartered in San Jose, California.

Augment Code is an AI-powered coding assistant built for professional software engineers and large codebases. Its Cosmos platform runs software agents at scale, providing context, tools, and feedback loops to improve development workflows. The company positions itself as purpose-built for enterprise-grade software development.

Backpack is a digital payments platform built specifically for higher education, replacing check-based workflows with electronic payment infrastructure. It handles 529 college savings plan payments, scholarships, and third-party payments for universities via API-driven payment gateways.

Bacon is a flexible work marketplace that connects gig workers with local companies for on-demand hourly shifts. Workers find and book single shifts through the Bacon app and receive quick payment upon completion. The platform serves both job seekers looking for flexible work and businesses needing on-demand hourly labor.

Bigleaf Networks is an SD-WAN and cloud networking company that provides a managed network optimization service for businesses, using a holistic wireless-first approach to boost application responsiveness and internet performance over commodity broadband circuits such as cable and DSL. The company markets its service under the Bigleaf Cloud Connect brand.

Biomotum is a medical device company that builds wearable robotic rehabilitation products designed to support clinicians in improving walking function for individuals with neurologic impairments. Its Spark device is a powered exoskeleton intended for rehabilitation and personal use by individuals with gait impairments.

Birch Finance was a San Jose-based fintech startup that helped consumers find the best credit cards and optimize rewards by analyzing their spending habits. Founded as a credit card rewards optimization app, it participated in TechCrunch Startup Battlefield and raised $1 million before being acquired by Even Financial in October 2018.

Birch Biosciences is a Portland, Oregon biotechnology company that develops novel plastic recycling technologies using generative AI and advanced enzyme engineering to bring plastics into the circular economy. Founded in 2021 by Johan Kers, the company is a Y Combinator-backed startup.