Ann Arbor healthcare VC — largest Michigan VC by AUM. Managing Partners: Jan Garfinkle, Tom Shehab, Dan Kidle. Six funds. Healthcare devices, diagnostics, services, IT. Capital-efficient companies cutting healthcare costs. Midwest preference. Notable: HistoSonics ($2.25B exit Q3 2024), BioIQ, Inogen, NeuMoDx.

Detroit mobility sector VC. Invests in entrepreneurs across air, land, sea, and space mobility. ISA (Infrastructure, Systems, Applications) Framework for Mobility 4.0. Global focus.

Farmington Hills (Metro Detroit) + UK transatlantic VC. $705M AUM. 30+ year history. Patient capital, advanced manufacturing, alternative energy, business services, consumer products, IT, life sciences, media, mobility. Notable: Socially Determined ($20M Series A 2025).

Detroit flagship early-stage VC. Founded by Dan Gilbert (Rocket Companies/Quicken Loans founder). $300M AUM. Partners: Jared Stasik, Jake Cohen. Seed and early-stage tech. Core to Dan Gilbert's downtown Detroit revitalization strategy. Rock Family of 90+ companies as portfolio support network. Notable: StockX (early), Tome Software.

Detroit + Boston mobility-focused VC. $275M AUM. Next-generation mobility: transportation, autonomous vehicles, freight, industrial, sustainability. 103 investments, 19 exits. $3M–$10M early stage, $100K–$500K seed. Notable: May Mobility, Asterion Systems.

GM corporate venture capital arm. Detroit Renaissance Center HQ. Invests in mobility, autonomous, electrification, and supply chain tech aligned with GM's transformation agenda.

Detroit early-stage community development VC. $50M+ AUM. $28M+ deployed, 200+ Michigan companies. Diversity-focused: 50%+ of investments in diverse founders. Enterprise SaaS, AI, life sciences, mobility. Notable: StockX (early rounds).

Detroit early-stage VC. $250M AUM. Business services, consumer, media, mobility. Close partner model — works directly with executive teams. Notable: Humatics, Inrix, Karamba Security, Life360, Lyft, Nutonomy, Ouster, ParkMobile.

Detroit fund of funds and direct investor. Catalyzed Michigan's VC ecosystem growth. Co-invests across the state. Notable: Banza growth round 2025.