Pure-play biotech VC spun out of Avalon Ventures in 2022. $135M Fund I. Managing Partners: Jay Lichter, Sandy Madigan, Tighe Reardon, Sergio Duron. Kevin Kinsella = Emeritus Partner. Incubation model with in-house labs. Notable exits: Nerio Therapeutics ($1.3B, Boehringer Ingelheim 2024), Calporta ($576M Merck).

La Jolla-based seed/early VC. $750M+ invested across 11 funds. Life sciences and tech. Founded by Kevin Kinsella. 125+ companies. Notable: Vertex, Synaptics, Vocera, Onyx Pharma. WSJ top biotech VC. [merged from 817]: San Diego's pioneering life sciences + tech VC. Founded 1983 by Kevin Kinsella. $750M+ deployed. Separate Avalon BioVentures fund ($135M, 2022) exclusively for early-stage biotech.

One of few VC firms investing primarily in defense technology. Menlo Park + San Diego offices. GP: Larsen Jensen. $125M fund (Dec 2023). 40+ companies. Deep SBIR expertise — helps portfolio from first SBIR contract through DoD scale. Close ties to Naval Base San Diego, Camp Pendleton, SOFWERX. Notable: Shield AI (early), Firestorm Labs, Kodiak ($50M Army project), Astranis, Solugen.

US Navy facilitation layer connecting startups and small businesses to Navy/Marine Corps operational needs. Not a traditional VC — channels solutions to naval requirements. Tech Bridges: regional network linking Naval Labs, warfare centers, industry, academia. San Diego is a primary hub given Naval Base San Diego (largest in US). Key entry point for maritime, C-UAS, and naval defense tech companie

Corporate VC arm of Qualcomm. US, China, India, Israel, Europe, LatAm, Korea. Managing Directors: Quinn Li, Carlos Kokron. Focus: mobile, wireless, AI, IoT, semiconductor. Notable: Cloudflare, Fitbit, SentinelOne, Zoom, Magic Leap, Airspace, Braincorp, Wiliot.

San Diego multi-stage VC. Founded by Bill Maris (ex-Google Ventures, managed $3B+, led Uber/Nest/Slack/23andMe). Partners: Bill Maris, Andy Harrison, Michael Pellini, Steve Kafka. Notable: Cue Health, CrowdStrike, Coinbase, Relay Therapeutics, Neuralink, Singular Genomics. [merged from 630]: Frontier technology VC founded by Bill Maris (founder of Google Ventures). AI, enterprise software, cybers